The AI-designed drug pipeline has grown to more than 170 in clinical development today, with 15-20 expected to reach pivotal trials this year. 

AI doesn’t have to improve clinical success rates for a bull case to play out in the AI-aligned biotechs. If it makes shots on goal cheaper by reducing the time and cost of identifying a preclinic

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TLDR

PONS runs ~78% of all token launches on Robinhood Chain, 2 weeks after the previous incumbent NOXA walked away.

The protocol is doing $170-180k/day in ETH revenue with ~24 cents of every fee dollar buying and burning PONS, and there’s no VC / team allocation or unlock overhang – mcap = FDV. It trades at ~0.62x annualized r

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The TAM for agents is massive, and it doesn’t rely on futuristic workflows or new behaviors. Agents will tackle the most dreaded aspects of our daily lives. Two examples:

• Passive shopping: you want an outdoor freezer, but only if it’s a great deal. Today that means manually checking retailers online and stopping by outlet stores every fe

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Summary

• The thing to be bearish on is positioning, not the cycle. Our cyclical macro regime is still risk-on, US growth leading indicators are resilient, recession probabilities are low, and equity breadth is broadening. None of that looks like a major top.

• What IS stretched is speculation itself: record leveraged ETF exposure, rec

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The 1W 9/21 EMA cross is a simple way to track momentum shifts. When the 9 crosses above the 21 on the weekly it means short-term momentum has overtaken the longer trend; usually a sign that a chart is transitioning from chop into an actual trend.

But not every cross is actionable. A cross tells you momentum shifted but it doesn’t tell yo

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Credit where credit is due. I’ve been deep in the crypto neobank trenches since Jan and tried every product out there. Vis a vis, Etherfi is squarely sitting at the pole position for me.

There are a handful of product hooks that make them stand out:

1) Borrow Mode

It’s an actual credit card. You can borrow against your assets and make pur

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We have another new free tool live here in the Delphi Portal: the crypto options dashboard. Crypto options are currently a $40B market spread across venues that sometimes price risk slightly differently. This dashboard pulls Deribit, OKX, Bybit, Bin... Read more

EtherFi started as a liquid restaking protocol. As the LRT landscape matured through 2024, providers converged: similar yields, similar security, little left to separate them at the protocol level. Competition shifted from technology to distribution, and EtherFi won that race. eETH was integrated across more than 400 DeFi protocols, maki

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Happy Friday! We have a new tool live here in the Delphi Portal, the RWA perp funding arb dashboard. 

This dashboard tracks funding rates across single-name stocks, equity indices, commodity, and fx perps on TradeXYZ, Lighter, Ostium, and Variational – purposefully the most liquid venues offering these products. With the high retail deman

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Preface: It’s October 2026, 4 months from now, GLM-6 was just released and it beats Fable-5.1 (the neutered re-release of the banned model) and it’s at par with Mythos on all the major benchmarks. The US government can’t shut it down so they issue... Read more